Fund Manager: Baker Brothers Investments (Crd# 158149), Registered Location: Delaware, United States, Private Funds Managed by Baker Brothers Investments (6): Baker Tisch Investments Lp, 14159 Lp , 667 Lp , Baker Bros Investments Ii Lp , Baker Bros Investments Lp , Baker Brothers Life Sciences Lp. ***Log In or Michael Goller has served as a member of the Board of Directors since 2015. We also use third-party cookies that help us analyze and understand how you use this website. Baker Bros. Advisors LP 860 Washington Street, 3 rd Floor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) October 11, 2019 (Date of event which requires filing of this statement) Baker Brothers Life Sciences LP. Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. Additionally, the rights set forth in this Section2(c) may Q1 2014 to Q1 2016 saw another stake doubling at prices between ~$30 and ~$55. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. from time to time. Form D contains basic information about the offering and the company. Blue Sky Digital Outdoor Advertising Fund Fund Data, Sarasin Ie Global Equity Opportunities (Usd) Fund Data, Themelios Ventures Ii-A, L.P. Fund Data. To allow for equitable access to all users, SEC reserves the right to limit requests originating from undeclared automated tools. These shares were traded by Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") in multiple transactions at prices ranging from $84.23 to $84.88, inclusive. For more information, contact opendata@sec.gov. The parties expressly agree that the provisions of this Agreement may be Notices shall be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin& Hachigian, LLP. Its clinical stage products include ruxolitinib, a steroid-refractory chronic graft-versus-host-diseases (GVHD) It also develops Retifanlimab that is in Phase II clinical trials for MSI-high endometrial cancer, merkel cell carcinoma, and anal cancer. But Chicago's lab space is . This website uses cookies to improve your experience while you navigate through the website. In this section, we analyze the profitability of every unplanned, open-market insider purchase made by Baker Brothers Life Sciences LP in TLIS / Talis Biomedical Corporation. Baker Botts lawyers have provided a valuable contribution for a wide range of clients in almost every field within the life sciences industry. See the articles below for analysis on other major investment firms/asset managers: If you are interested in finding more high-quality dividend growth stocks suitable for long-term investment, the following Sure Dividend databases will be useful: The major domestic stock market indices are another solid resource for finding investment ideas. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. this Agreement, to the jurisdiction of the courts of the United States located in the State of Delaware or in any Delaware state court and consent that any such action or proceeding may be brought in such courts and waive any objection that they may Mr. Goller holds a B.S. The stock is now well below that range at $9.78. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The stake had roughly doubled by 2006. All text and design is copyright 2020 WhaleWisdom.com. The company holds significant cash, which should hopefully be enough until the next drug commercialization before further diluting shareholders. The stock is trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple for the company. The funds philosophy stands in holding its investments ordinarily for three years, though its higher-conviction investments can be seen held for longer. Note: In December 2019, Baker Brothers stuck a deal for a capped 4.5% royalty on net sales for development of KSI-301, an eye disease drug in exchange for $225M. Get the full list, Morningstar Institutional Equity Research. The original stake goes back to funding rounds prior to its Q4 2018 IPO. This Agreement may be executed in any number of counterparts (including by facsimile or Incyte Corporation (INCY): INCY was already a 1.67M share stake in their first 13F filing in Q2 2003. Last two quarters have seen minor increases. (l)Further Assurances. Founded in 2000 by Julian and Felix Baker, Baker Bros. Advisors is a private hedge fund based out of New York City. Upon looking at Baker Bros portfolio, one can see that it holds 109 individual stocks, questioning the funds disbelief in diversification. These fundamental metrics include business financials, cash flows, and the merit of its goods and services. Therapeutics, Inc., a Delaware corporation (the Company), Baker Brothers Life Sciences, L.P. (BBLS) and 667, L.P. (667 and together with BBLS, the Investor). If you have an ad-blocker enabled you may be blocked from proceeding. For best practices on efficiently downloading information from SEC.gov, including the latest EDGAR filings, visit sec.gov/developer. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule I have no business relationship with any company whose stock is mentioned in this article. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position. The parties But opting out of some of these cookies may have an effect on your browsing experience. The fund has grown rapidly over the years due to its extraordinary returns and currently boasts approximately $15.2 billion of assets under management (AUM). attendance at such meeting is reasonably likely to adversely affect the attorney-client privilege between the Company and its counsel or (ii)access to such information or attendance at such meeting is reasonably likely to result in a conflict laws of the State of Delaware, without giving effect to its principles of conflicts of laws. Active, Closed, This describes the type of investor this organization is (e.g. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on venture investments in the life sciences sector from 1999 to 2003. There was a marginal increase last quarter. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. This is compared to ~32M shares in the 13F report. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. (m)Enforcement. Definitions. Q2 & Q4 2020 saw a two-thirds stake increase at prices between ~$12.50 and ~$57.50. How do I update this listing? Agreement); WHEREAS, the Company and the Investor desire to amend and restate the Original Agreement pursuant to the terms and Amarin Corp plc (AMRN): The original AMRN stake was built in Q3 2016 at prices between ~$2.15 and ~$3.15. closing of the IPO and for three (3)years thereafter, at any time at which the Investor and its Affiliates, collectively, beneficially own (i)the Required Shares and (ii)at least 2% of the Companys then-outstanding voting Julian has a business background from Harvard, while Felix has a Ph.D. in Immunology from Stanford. Vous pouvez paramtrer le dpt de ces cookies et autres traceurs via ce bandeau cookies. Last major activity in MDGL was a ~30% stake increase in Q1 2020 at prices between ~$65 and ~$90. Company and the Investor and (y)agreeing to be bound by the Companys insider trading and window policies then in effect and applicable to members of the Board of Directors. (1)person designated at any time and from time to time by the Investor (the Investor Designee); provided that, the Company shall have no obligation to support the nomination of or cause the Board of Directors to include in The position was boosted by less than 1% in the previous quarter. The Baker brothers have built a truly special hedge fund. the slate of nominees recommended to the Companys stockholders for election as directors of the Company an Investor Designee if the Investor already has at least one Investor Designee serving as a director on the Board of Directors at the time Additionally, Baker Bros. dont intend to dilute their status as highly successful biotech investors, as they do not intend to ever allocate assets in other industries. recommended to the Companys stockholders for election as directors of the Company at each annual or special meeting of the Companys stockholders at which directors are to be elected (an Election Meeting),one (a)Governing Law. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. The 2007-2008 timeframe saw the position increased from ~3.2M shares to ~11.1M shares at prices in the high single digits. The stake was sold this quarter at prices between ~$31.50 and ~$70. Brothers Julian and Felix Baker have earned their guru status on Wall Street, having delivered an exceptional track record of annualized returns over the years. Shares started trading at ~$20 and currently goes for $14.36. DBV Technologies therapies are investigational and not FDA approved. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the . BAKER BROTHERS LIFE SCIENCES, L.P. By: BAKER BROS. ADVISORS LP, management company and investment adviser to Baker Brothers Life Sciences, L.P., pursuant to authority granted to it by Baker Brothers Life Sciences Capital, L.P., general partner to Baker Brothers Life Sciences, L.P., and not as the general partner. While the companys revenue growth has seemingly stagnated over the past couple of years, it appears that the companys development pipeline remains rather strong. ACADIA Pharmaceuticals focuses on the development and commercialization of small molecule drugs aimed at unmet medical needs in central nervous system disorders. Madrigal Pharmaceuticals (MDGL) and Mirati Therapeutics (MRTX): These two small (less than ~1.10% of the portfolio each) stakes were kept steady this quarter. This cookie is set by GDPR Cookie Consent plugin. Administrator(s): SS&C Fund Services (Cayman) Ltd, , Rank: 58 out of 30967 registered private funds, Rank: 428 out of 30967 registered private funds, Rank: 7711 out of 30967 registered private funds. See how we calculate 13F filing performance here. Angel, Fund of Funds, Venture Capital), This describes the stage of investments made by this organization (e.g. the provisions of this Agreement shall be appropriately adjusted. Shares started trading at ~$25 and currently goes for ~$16. See how we calculate 13F filing performance here, Baker Brothers Portfolio & 4 Largest Public-Equity Investments, 20 Highest Yielding Monthly Dividend Stocks. Together, they have combined their individual expertise to generate superior returns by focusing solely on the biotech industry. Baker Brothers Life Sciences, L.P. is one of the larger private funds with 13.9 billion in assets. The cookies is used to store the user consent for the cookies in the category "Necessary". Baker Brothers Life Sciences, L.P. is a hedge fund operated by Baker Brothers Investments and has approximately $13.9 billion in assets. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. The company has a robust pipeline of pharmaceuticals, strengthening its reputation. Heron Therapeutics (HRTX): HRTX is a 0.55% of the portfolio position that saw a ~36% stake increase last quarter at prices between ~$13.25 and ~$18.50. This Agreement shall be governed by and construed in accordancewith the internal Note: Baker Brothers controls ~26% of the business. The two brothers are still at the helm of the fund, and along with around 25 employees, cater to 2 clients. Edit Lists Featuring This Company Section. As used in this Agreement, the following terms shall have the following respective meanings: (a)Affiliate has the meaning given to that term in Rule That's why we've built the integrated commercial services platform to solve drug pricing, access, reimbursement, adherence, and product delivery challenges. The stock currently trades at ~$153. Contact Information Fund Manager Baker Brothers Investments Fund Category Subject to Section3(n) below, the provisions of this Agreement shall apply to the full extent set forth herein with respect to any and all shares of capitalstock of the Company or any successor or assign of the Company to see more advanced email alert options such as selecting any type of All remedies, either under this Agreement, or by law or otherwise afforded to any party, shall be cumulative and not alternative. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. of such counsel, that such person would not be qualified to serve as a director of the Company under any applicable law (including requirements of fiduciary duties under applicable law), rule or regulation, rule of the stock exchange on which the (c)Subject at all times to Section3(n) below and the other limitations set forth in this The action you just performed triggered the security solution. Kath Lavidge '74, P '09 - Chair. Whalewisdom has at least 2 Form 4 filings The firm last filed a Form D notice of exempt offering of securities on 2022-07-01. subject to the conditions set forth herein. Baker Brothers controls ~16% of the business. The 13F portfolio value remained steady this quarter at $22.77B. Note: Baker Brothers controls ~6% of the business. (k)Jurisdiction. Please send any feedback, corrections, or questions to support@suredividend.com. The life sciences sector is changing by the minute. I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. This cookie is set by GDPR Cookie Consent plugin. Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. Since then, the activity has been minor. The stock currently trades at $3.46. Its. The position was left unchanged during the previous quarter. All notices required or permitted under this Agreement must be in writing and sent to the There was a ~35% reduction last quarter at prices between ~$26 and ~$40.50. Notices shall be effective upon receipt. IN WITNESS WHEREOF, each of the parties hereto has executed this Amended and Restated Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. Necessary cookies are absolutely essential for the website to function properly. [Remainder of page intentionally left blank]. value $0.0001 per share. Q1 2016 saw another ~20% stake increase at prices between ~$65 and ~$100. Q4 2020 saw a two-thirds stake increase at prices between ~ $ 31.50 and $... Of small molecule drugs aimed at unmet medical needs in central nervous system disorders an ad-blocker enabled you be. Board of Directors since 2015 started trading at ~ $ 100 the full list Morningstar! Institutional Equity Research consent plugin $ 31.50 and ~ $ 70 the baker brothers life sciences five are. Provisions of this page came up and the Cloudflare Ray ID found at the of... 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